Pediatric tuberculosis in India: Justice and human rights

Kinsey Mannebach1, Anne Dressel2, Leighann Eason2

  • 1Joseph J Zilber School of Public Health, University of Wisconsin-Milwaukee, Minneapolis, Minnesota, USA.

Insights

Tuberculosis (TB) disproportionately affects children in India. Addressing root causes like poverty and improving sanitation are crucial for primary prevention of this infectious disease.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Pediatrics

Background:

  • Tuberculosis (TB) remains the leading infectious cause of death globally, with India bearing a significant burden.
  • Vulnerable populations, including pregnant women and children, face heightened risks and diminished self-protection against TB.
  • Factors like malnutrition, HIV, air pollution, maternal education, healthcare access, poverty, and sanitation influence TB susceptibility and severity.

Purpose of the Study:

  • To highlight the critical need for primary prevention strategies for pediatric tuberculosis in India.
  • To shift focus from clinical and tertiary prevention to upstream determinants of health.
  • To advocate for evidence-based interventions addressing social and environmental factors contributing to pediatric TB.

Main Methods:

  • Literature review focusing on clinical and upstream factors influencing TB.
  • Analysis of risk factors, including socioeconomic, environmental, and healthcare access determinants.
  • Examination of current prevention strategies, emphasizing the gap in primary prevention.

Main Results:

  • Existing literature predominantly focuses on clinical aspects and secondary/tertiary prevention (case finding, treatment).
  • Upstream factors such as wealth equity, environmental regulation, maternal education, sanitation, and healthcare access are underemphasized.
  • Pediatric TB in India is influenced by a complex interplay of socioeconomic and environmental determinants.

Conclusions:

  • Primary prevention strategies, including improved sanitation, air quality monitoring, women's education, and enhanced healthcare access, are cost-effective for pediatric TB in India.
  • Public health professionals must advocate for vulnerable populations and address the social justice and human rights dimensions of TB.
  • Addressing root causes is essential for combating extremely drug-resistant TB and preventing cross-border infectious disease spread.

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