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Published on: September 20, 2018
Ocular Complications of Pediatric Inflammatory Bowel Disease: A Case Series From a Pediatric Tertiary Medical Center
Pejman Rohani1, Fatemeh Abdollah Gorji1,2, Mohammad Eshaghi1
1Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Insights
Ocular manifestations are common in children with inflammatory bowel disease (IBD). Annual eye screenings are recommended for pediatric IBD patients to detect these sight-threatening complications early.
Area of Science:
- Ophthalmology
- Pediatrics
- Gastroenterology
Background:
- Ocular extraintestinal manifestations (O-EIMs) are a significant concern in pediatric inflammatory bowel disease (IBD).
- This study investigated the prevalence of O-EIMs in children diagnosed with IBD.
- Data was collected from Mofid Children's Hospital, Tehran, Iran, between 2014 and 2019.
Observation:
- The study included 96 pediatric patients under 18 years old with IBD who were referred for ophthalmological examination.
- Four patients exhibited ocular manifestations directly related to IBD.
- Two patients experienced ocular complications secondary to IBD treatment.
Findings:
- Anterior uveitis was the most frequent O-EIM, observed in 3 (50.0%) patients.
- Episcleritis occurred in 1 (16.7%) patient.
- Posterior subcapsular cataract was diagnosed in 2 (33.3%) patients.
Implications:
- O-EIMs represent a critical aspect of managing pediatric IBD.
- Routine annual ophthalmological screening is crucial for early detection and management of ocular complications in children with IBD.
- Proactive screening can help prevent vision impairment in this vulnerable population.
Abstract:
Background. Ocular extraintestinal manifestations (O-EIMs) are one of the most well-known EIMs in patients with inflammatory bowel disease (IBD). This study aimed to identify the frequency of O-EIMs in children with IBD, referred to Mofid Children's Hospital, Tehran, Iran, during 2014 to 2019. Methods. Children with IBD, younger than the age of 18 years, who were referred to an ophthalmologist, were included in this study. Results. Ninety-six patients with IBD were examined. Four patients had ocular manifestation of IBD. Two patients had complications due to treatment of IBD. The mean age of the patients was 11.25 ± 4.17 years (range: 5.5-17 years). The O-EIMs included 3 (50.0%) cases of anterior uveitis, 1 (16.7%) case of episcleritis, and 2 (33.3%) cases of posterior subcapsular cataract. Conclusion. O-EIMs are important in children with IBD. Therefore, it is recommended that annual screening for ocular complications be performed in all children with IBD.
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