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Liquid Biopsy, Diagnostic Imaging, and Future Synergies
Milena Petranovic1, Sana Raoof2, Subba R Digumarthy3
1Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts; Director of Quality, Division of Thoracic Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts.
Liquid biopsies, analyzing circulating free DNA, complement cancer imaging. This study explores their synergy in non-small-cell lung cancer care, from early detection to disease monitoring.
Area of Science:
- Oncology
- Radiology
- Molecular Diagnostics
Background:
- Medical imaging is crucial for cancer diagnosis and patient management.
- Liquid biopsies, analyzing circulating free DNA, offer a minimally invasive approach.
- Integrating these modalities can enhance cancer care across the continuum.
Purpose of the Study:
- To examine the role of liquid biopsies in non-small-cell lung cancer (NSCLC) care.
- To highlight how liquid biopsies are transforming clinical practice.
- To explore future collaborations between liquid biopsy and imaging.
Main Methods:
- Review of current literature on liquid biopsy and cancer imaging.
- Case studies focusing on non-small-cell lung cancer.
- Analysis of clinical practice changes and future potential.
Main Results:
- Liquid biopsies are increasingly vital in NSCLC diagnosis and monitoring.
- Synergies exist in early detection, screening, and treatment response assessment.
- Clinical practice is evolving to incorporate liquid biopsy alongside imaging.
Conclusions:
- Liquid biopsies are essential complementary tools in oncology.
- The integration of liquid biopsy and imaging promises improved cancer care.
- Future research should focus on optimizing combined diagnostic and monitoring strategies.
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