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Hydroxyzine Use in Preschool Children and Its Effect on Neurodevelopment: A Population-Based Longitudinal Study

Hans J Gober1,2, Kathy H Li3,4, Kevin Yan1

  • 1Division of Translational Therapeutics, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

Frontiers in Psychiatry
|February 14, 2022
PubMed
Summary

First-generation antihistamine hydroxyzine use in young children was linked to higher rates of mental and psychomotor disorders, including tics and anxiety, up to age 10. Further research is needed to confirm causality and hydroxyzine safety in pediatric populations.

Keywords:
antihistamineatopic dermatitishydroxyzinelongitudinal studymental disordersneurodevelopmental disorderspreschool-age childrentics

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