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Related Experiment Videos

Brain gliomas: sonographic characterization.

J P McGahan, W G Ellis, R W Budenz

    Radiology
    |May 1, 1986
    PubMed
    Summary
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    Ultrasound (US) precisely locates brain tumors and enhances characterization beyond CT scans. For gliomas, the echogenic margin is the optimal biopsy site, avoiding necrotic centers.

    Area of Science:

    • Neurosurgery
    • Medical Imaging
    • Oncology

    Background:

    • Accurate characterization of intracerebral gliomas is crucial for effective treatment planning.
    • Computed tomography (CT) provides valuable preoperative information but may have limitations in real-time intraoperative guidance.
    • Determining the optimal biopsy site is essential for obtaining diagnostic tissue and improving patient outcomes.

    Purpose of the Study:

    • To evaluate the utility of intraoperative ultrasound (US) in characterizing brain lesions, specifically intracerebral gliomas.
    • To compare sonographic findings with preoperative CT, gross intraoperative observations, and histopathology.
    • To identify the most suitable site for biopsy in gliomas using intraoperative US.

    Main Methods:

    • Intraoperative sonographic examination was performed on nine intracerebral gliomas.

    Related Experiment Videos

  • Sonographic findings were correlated with preoperative CT, gross intraoperative findings, and histopathologic results.
  • Ultrasound and CT data were analyzed for lesion localization and characterization capabilities.

    • Main Results:

    • Real-time US accurately localized intracerebral neoplasms in all cases.
    • Gliomas appeared echogenic compared to surrounding brain tissue on US.
    • US effectively characterized cystic components and identified necrotic areas, guiding surgical decisions.
    • The echogenic margin of the tumor, representing active growth, was identified as the optimal biopsy site.

    Conclusions:

    • Intraoperative ultrasound is a precise and rapid tool for localizing intracerebral gliomas.
    • US complements CT by providing additional information for tumor characterization and biopsy site selection.
    • Combining preoperative CT and intraoperative US improves lesion characterization and prediction of the best biopsy site.