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A Case Report on Atypical Presentation of Metastatic Prostate Cancer
Anthony Lyonga Ngonge1, Stacy N Amadife1, Felix W Wireko1
1Internal Medicine, Howard University Hospital, Washington, DC, USA.
Cureus
|February 14, 2022
Summary
Prostate cancer rarely spreads to the lungs, but this case highlights the importance of considering it. Early detection and treatment of metastatic prostate cancer to the lung are crucial.
Area of Science:
- Oncology
- Pulmonology
- Urology
Background:
- The lung is a frequent site for metastasis from colorectal and breast cancers.
- Metastatic lung cancer requires different treatment than primary lung cancer, necessitating accurate diagnosis.
- Prostate cancer is an uncommon cause of lung metastasis.
Observation:
- A patient presented with a solitary lung nodule, initially suspected to be primary lung cancer due to risk factors.
- The patient later developed additional lung nodules and bone involvement.
- Imaging revealed new lung nodules and pleural effusion, alongside pelvic bone metastasis.
Findings:
- The patient was diagnosed with metastatic prostate cancer to the lung.
- Treatment included gonadotropin-releasing hormone therapy, leading to a decrease in prostate-specific antigen (PSA) levels.
- Surgical resection of lung nodules was performed.
Implications:
- This case underscores that prostate cancer can metastasize to the lungs, though infrequently.
- Clinicians should maintain a high index of suspicion for lung nodules in patients with a history of prostate cancer.
- Distinguishing between primary and metastatic lung cancer is critical for appropriate patient management.

