Perinatal Opioid Use Disorder Research, Race, and Racism: A Scoping Review

Davida M Schiff1, Erin C Work1, Bridget Foley2

  • 1Division of General Academic Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts.

Pediatrics
|February 14, 2022
PubMed

Insights

Racial and ethnic disparities persist in maternal-infant health and opioid use disorder (OUD) treatment. This review found poor reporting of race/ethnicity data, hindering efforts to achieve health equity for affected dyads.

Area of Science:

  • Perinatal Health
  • Health Equity Research
  • Substance Use Disorders

Background:

  • Racial and ethnic inequities are prevalent in maternal-infant health and substance use disorder treatment.
  • Opioid use disorder (OUD) in pregnant individuals and its impact on infants present significant public health challenges.
  • Understanding disparities in care and outcomes is crucial for addressing these inequities.

Purpose of the Study:

  • To systematically review research on maternal-infant dyads affected by OUD.
  • To evaluate racial/ethnic disparities in health utilization and outcomes.
  • To critically assess the reporting and inclusion of race/ethnicity data in OUD research.

Main Methods:

  • Systematic review of peer-reviewed literature from MEDLINE, Embase, and Web of Science (2000-2020).
  • Included studies reporting health utilization and outcomes for dyads affected by OUD from pregnancy through the infant's first birthday.
  • Extracted data on race/ethnicity, study exposures/outcomes, data analysis, and discussion of findings related to race/ethnicity and racism.

Main Results:

  • Of 2023 articles reviewed, 152 quantitative and 17 qualitative studies were included.
  • Few studies (3/152 quantitative) explicitly evaluated racial/ethnic differences among dyads.
  • Race/ethnicity data were poorly reported; many studies mentioned race/ethnicity but few analyzed or adjusted for it, and none discussed racism's role.

Conclusions:

  • Few studies are designed to evaluate racial/ethnic inequities in perinatal OUD.
  • Inadequate reporting and analysis of race/ethnicity data impede understanding of disparities.
  • Prioritizing inclusion of marginalized groups and addressing structural racism is essential for achieving health equity in perinatal OUD care.
Abstract

Related Concept Videos

Stereotypes, Prejudice, and Discrimination02:55

Stereotypes, Prejudice, and Discrimination

Humans are very diverse and although we share many similarities, we also have many differences. The social groups we belong to help form our identities (Tajfel, 1974). These differences may be difficult for some people to reconcile, which may lead to prejudice toward people who are different. Prejudice is a negative attitude and feeling toward an individual based solely on one’s membership in a particular social group (Allport, 1954; Brown, 2010). Prejudice is common against people who...
92.1K
Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
883
Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
477
Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
423