A Benzothiadiazole-Based Eu³⁺ Metal-Organic Framework as the Turn-On Luminescent Sensor toward Al³⁺ and Ga³⁺ with Potential Bioimaging Application

The design and preparation of novel multifunctional lanthanide metal-organic frameworks (Ln-MOFs) have been arisen widespread attention. In particular, Ln-MOFs have shown great luminescence potential in chemical sensing. Herein, a new benzothiadiazole-based Eu-MOF {[(CH₃)₂NH₂][Eu(BTDB)₂]·2H₂O} (JXUST-11) was obtained based on 4,4'-(benzo[c][1,2,5]thiadiazole-4,7-diyl)dibenzoic acid (H₂BTDB), which exhibits a chain-based three-dimensional framework. Moreover, JXUST-11 is considered as a photoluminescent sensor to identify Al³⁺ and Ga³⁺ ions by fluorescence enhancement with the detection limits of 2.9 and 10.2 ppm, severally. Importantly, Al³⁺ and Ga³⁺ can be discerned with the naked eye by color change under a natural lamp. In addition, a portable MOF film based on JXUST-11 was developed for Al³⁺ and Ga³⁺ detection. This is the first Ln-MOF that can be employed as a naked-eye fluorescent probe to identify Ga³⁺. Interestingly, JXUST-11 is also capable of detecting Al³⁺ and Ga³⁺ in living cells.