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Updated: Oct 3, 2025

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials
Published on: March 3, 2023
Can We Approach a Zero Percent Infection Rate In Total Knee Arthroplasty? A Program To Achieve This Goal With
Paul W Knapp1, Zhongming Chen1,2, Matthew F Myntti3
1Northwell Health Orthopaedics, Lenox Hill Hospital, New York, New York.
Abstract:
Periprosthetic joint infections (PJIs) are one of the most feared complications in the realm of adult reconstruction due to the substantial morbidity and mortality associated with these cases. Advancements in arthroplasty have been made across a variety of areas of interest including implant surfaces, implant design, material science, etc., but a focus on infection prevention and treatment is of utmost importance. A new technology has been created that targets biofilm and aims to prevent infection in total joint arthroplasty. In this manuscript we aim to describe the benefits of this technology and describe the ideal use in a case scenario format. We believe that with this technology that we can approach the goal of a zero periprosthetic infection rate.
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