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Orchidaceae-Derived Anticancer Agents: A Review.

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Orchids contain potential anticancer compounds, but their bioactive substances are not well-identified. Further research on diverse orchid species is crucial for unlocking their antitumor potential.

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Area of Science:

  • Pharmacognosy
  • Ethnobotany
  • Medicinal Chemistry

Background:

  • Orchidaceae is a large flowering plant family with traditional medicinal uses.
  • Orchids are used in folk medicine for infections and tumors.
  • The chemical composition and anticancer properties of orchids are largely unknown.

Purpose of the Study:

  • To review recent literature on orchid-derived bioactive substances with anticancer properties.
  • To assess the current state of research on the anticancer activity of Orchidaceae.
  • To identify research gaps and future directions.

Main Methods:

  • Literature review of papers published since 2015.
  • Exploration of electronic databases for relevant studies.
  • Analysis of identified orchid-derived bioactive substances and their anticancer activities.

Main Results:

  • Many orchid species contain potential antitumor chemicals.
  • The bioactive substances of a limited number of orchids have been identified.
  • Most studies focus on Asian orchid taxa.

Conclusions:

  • Orchids possess significant anticancer potential.
  • Identification of bioactive substances and broader research on American and African species are needed.
  • Correct sample identification is essential for future studies.