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Related Experiment Video

Updated: Oct 3, 2025

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria

Published on: June 27, 2022

Buffering Adaptive Immunity by Hydrogen Sulfide.

Giulia Pozzi¹, Giuliana Gobbi¹, Elena Masselli^1,2

¹Anatomy Unit, Department of Medicine and Surgery, University of Parma, Via Gramsci 14, 43126 Parma, Italy.

|February 15, 2022

Summary

Hydrogen sulfide (H2S) acts as a crucial mediator in immune responses, balancing T helper cell populations (Th1, Th2, Th17, Treg). This review explores H2S

Keywords:

NaHS cystathionine-lyase cystathionine-synthase gasotransmitters sulphurous waters

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Published on: September 29, 2019

Area of Science:

Immunology and biochemistry, focusing on cellular signaling and immune regulation.

Background:

Adaptive immunity relies on T cell populations (Th1, Th2, Th17, Treg) orchestrated by various stimuli.
Hydrogen sulfide (H2S) is an endogenous and exogenous mediator influencing immunological responses and diseases.

Purpose of the Study:

To comprehensively review the role of H2S in maintaining immune balance.
To elucidate H2S's function as a natural buffer for T cell responses.

Main Methods:

Review of existing literature on H2S and immune cell signaling.
Analysis of H2S's impact on T cell activation, proliferation, and cytokine modulation.

Main Results:

H2S modulates key cell signaling pathways in immune cells like monocytes and T cells.
H2S influences T cell activation, survival, proliferation, polarization, adhesion, and cytokine production.

Conclusions:

H2S acts as a natural buffer, maintaining functional balance among Th1, Th2, Th17, and Treg cells.
Understanding H2S's role is critical for managing inflammatory and autoimmune conditions.