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Interpolymer Complexes of Poly(methacryloyloxyethyl phosphorylcholine) and Polyacids
Tatiana Nekrasova1, Olga Nazarova1, Elena Vlasova1
1Institute of Macromolecular Compounds, Russian Academy of Sciences, Bolshoi Pr. 31, 199004 St Petersburg, Russia.
Polymers
|February 15, 2022
Summary
Poly(methacryloyloxyethyl phosphorylcholine) forms interpolymer complexes with carboxylic acids and poly(vinylphosphonic) acid via hydrogen bonds. These complexes show altered polymer chain mobility, indicating significant structural changes.
Area of Science:
- Polymer Chemistry
- Supramolecular Chemistry
- Biomaterials Science
Background:
- Poly(methacryloyloxyethyl phosphorylcholine) (PMPC) is a biocompatible polymer with potential in various applications.
- Interpolymer complex formation is a key phenomenon in polymer science, influencing material properties.
- Understanding the interactions between PMPC and other polymers is crucial for designing advanced materials.
Purpose of the Study:
- To investigate the formation of interpolymer complexes between PMPC and polymers containing carboxylic acid groups or poly(vinylphosphonic) acid.
- To elucidate the role of hydrogen bonding and hydrophobic interactions in stabilizing these complexes.
- To characterize the structural and dynamic changes occurring upon complex formation.
Main Methods:
- Synthesis of luminescent-labeled PMPC and copolymers.
- Investigation of interpolymer complex formation in aqueous solutions.
- Application of polarized luminescence and infrared (IR) spectroscopy.
- Determination of nanosecond relaxation times to assess polymer chain dynamics.
Main Results:
- PMPC forms hydrogen-bonded interpolymer complexes with polycarboxylic acids and poly(vinylphosphonic) acid.
- Complex formation significantly alters polymer chain mobility, with relaxation times changing by a factor of 2-50.
- Hydrogen bonds are the primary driving force, with hydrophobic interactions providing additional stabilization.
- The PMPC/poly(vinylphosphonic) acid complex exhibits a looser structure compared to PMPC/polycarboxylic acid complexes due to electrostatic repulsion.
Conclusions:
- Hydrogen bonding is the dominant interaction in PMPC-based interpolymer complexes.
- The structural and dynamic properties of these complexes are highly tunable.
- PMPC shows versatility in forming complexes with various polyelectrolytes, offering potential for novel material design.
Keywords:
interpolymer complexesintramolecuar mobilitypoly(2-methacryloyloxyethyl phosphorylcholine)poly(carboxylic acids)poly(vinylphosphonic acid)More Related Videos
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