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Intracardiac thrombi and systemic embolization.

R S Meltzer, C A Visser, V Fuster

    Annals of Internal Medicine
    |May 1, 1986
    PubMed
    Summary
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    Echocardiography aids in diagnosing intracardiac thrombi. Anticoagulants reduce thrombi and emboli in myocardial infarction and dilated cardiomyopathy, but not typically in left ventricular aneurysm.

    Area of Science:

    • Cardiology
    • Medical Imaging

    Background:

    • Intracardiac thrombi are diagnosed and their natural history traced using echocardiography.
    • Left ventricular thrombi are associated with acute myocardial infarction, left ventricular aneurysm, and idiopathic dilated cardiomyopathy, leading to emboli.

    Purpose of the Study:

    • To review the role of echocardiography in diagnosing left ventricular thrombi.
    • To assess the efficacy of anticoagulation in preventing emboli in different clinical conditions.

    Main Methods:

    • Echocardiographic studies were reviewed.
    • Clinical outcomes related to left ventricular thrombi and anticoagulation were analyzed.

    Main Results:

    • One-third of patients with acute anterior myocardial infarction have left ventricular thrombi; anticoagulation decreases thrombi and emboli.

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  • Protruding and mobile thrombi are more likely to embolize.
  • Anticoagulation is recommended for idiopathic dilated cardiomyopathy, irrespective of thrombus location.
  • Anticoagulation is not sufficiently indicated for chronic left ventricular aneurysm, despite common thrombus presence.

    • Conclusions:

    • Echocardiography is crucial for identifying intracardiac thrombi and guiding treatment.
    • Anticoagulation is beneficial in acute myocardial infarction and idiopathic dilated cardiomyopathy.
    • The role of anticoagulation in left ventricular aneurysm requires further investigation.