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Development of New Experimental Dental Enamel Resin Infiltrants-Synthesis and Characterization
Doina Prodan1, Marioara Moldovan1, Andrea Maria Chisnoiu2
1"Raluca Ripan" Institute for Research in Chemistry, Babes-Bolyai University, 30 Fantanele Street, 400294 Cluj-Napoca, Romania.
Materials (Basel, Switzerland)
|February 15, 2022
Summary
Researchers developed new dental infiltrants for white spot lesions, showing high conversion rates and mechanical strength. The best formulations, P2 and P2F, offer promising alternatives for treating early tooth decay.
Area of Science:
- Dental Materials Science
- Polymer Chemistry
- Restorative Dentistry
Background:
- Dental white spots represent early enamel demineralization, necessitating effective minimally invasive treatments.
- Current infiltration techniques aim to arrest lesion progression and improve aesthetics.
- Development of novel infiltrant materials with enhanced properties is crucial for improved clinical outcomes.
Purpose of the Study:
- To synthesize and characterize experimental dental infiltrants for treating white spot lesions.
- To evaluate the degree of conversion, mechanical strength, water sorption, and fluoride release of new infiltrants.
- To compare the performance of experimental infiltrants against a commercial product (Icon).
Main Methods:
- Two series of experimental infiltrants (P1-P6 and P1F-P6F) were formulated using different monomer mixtures, with and without glass filler.
- Key properties including degree of conversion (DC), flexural strength, water sorption (WS), and fluoride release were measured.
- Residual monomer content was assessed for fluoride-releasing infiltrants; comparisons were made with the commercial Icon infiltrant.
Main Results:
- Experimental infiltrants exhibited high degrees of conversion (58.27-89.70% without filler, 60.62-89.99% with filler), surpassing Icon (46.94%).
- The highest flexural strengths were achieved with Bis-GMA/HEMA/TEGDMA based infiltrants (133.94 ± 16.389 MPa / 146.31 ± 7.032 MPa).
- Fluoride release was influenced by polymer matrix permeability and water sorption, potentially affecting residual monomer levels.
Conclusions:
- Experimental infiltrants demonstrated superior conversion and mechanical properties compared to the commercial Icon infiltrant.
- Formulations P2 and P2F (Bis-GMA/HEMA/TEGDMA based) showed the most promising results for dental white spot treatment.
- The developed infiltrants represent a viable advancement in minimally invasive restorative dental materials.
