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Related Experiment Videos

The cardiac donor: a six-year experience.

R W Emery, R C Cork, M M Levinson

    The Annals of Thoracic Surgery
    |April 1, 1986
    PubMed
    Summary

    Local cardiac organ procurement significantly improves patient survival compared to regional or distant options. This study highlights the benefits of shorter ischemic times for heart transplant recipients.

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    Area of Science:

    • Cardiology
    • Transplant Surgery
    • Organ Procurement

    Background:

    • Cardiac donor referrals were analyzed from March 1979 to March 1985.
    • Donor causes of death included motor vehicle accidents, gunshot wounds, and head injuries.

    Purpose of the Study:

    • To evaluate the impact of cardiac allograft procurement distance on patient survival.
    • To analyze factors influencing donor acceptance and organ utilization.

    Main Methods:

    • Retrospective review of 223 cardiac donor referrals.
    • Categorization of donors into local, regional, and distant procurement groups.
    • Survival analysis comparing outcomes based on organ procurement distance.

    Main Results:

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  • Local procurement (n=15) showed superior patient survival (median 59 months, 2-year survival 85%) compared to regional (n=23; 18 months, 43%) and distant (n=24; 21 months, 38%) procurement.
  • ABO compatibility was a major reason for donor refusal (50 patients).
  • Two regional grafts failed due to donor sepsis and inotropic support.

    • Conclusions:

    • Locally procured donor hearts are associated with significantly better long-term patient survival.
    • Shorter ischemic times and potentially better donor management in local procurements may contribute to improved outcomes.
    • Organ procurement distance is a critical factor in heart transplant success.