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Related Experiment Video

Updated: Oct 3, 2025

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response
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SARS-CoV-2 Detection Using Optical Fiber Based Sensor Method.

Muhammad Usman Hadi1, Menal Khurshid2

  • 1School of Engineering, Ulster University, Newtownabbey BT37 0QB, UK.

Sensors (Basel, Switzerland)
|February 15, 2022
PubMed
Summary
This summary is machine-generated.

A new plastic optical fiber (POF) U-shaped probe rapidly detects SARS-CoV-2, including Omicron variants, within 15 minutes. This low-logistics method offers faster, cheaper COVID-19 diagnosis, especially for remote areas.

Keywords:
COVID-19COVID-19 detectionPCRSARS-CoV-2U-shaped probeoptical fiber sensor

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Area of Science:

  • Biomedical Engineering
  • Optoelectronics
  • Infectious Disease Diagnostics

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, necessitates rapid and accessible diagnostic tools.
  • Emerging variants like Omicron present ongoing challenges for containment and require swift identification.
  • Current diagnostic methods can be time-consuming and require specialized laboratory infrastructure.

Purpose of the Study:

  • To develop a novel, rapid, and low-logistics diagnostic method for SARS-CoV-2 detection.
  • To assess the efficacy of a plastic optical fiber (POF) U-shaped probe for identifying COVID-19 and its variants.
  • To enable faster and more accessible clinical diagnosis, particularly in resource-limited settings.

Main Methods:

  • A U-shaped probe utilizing plastic optical fiber (POF) was designed for sample collection (oropharyngeal/nasopharyngeal).
  • The POF probe was integrated with a laser source and a photodetector for signal detection and analysis.
  • Comparative detection was performed using POF sensors with 200 µm and 500 µm diameters.

Main Results:

  • The POF U-shaped probe demonstrated accurate detection of SARS-CoV-2, including the Omicron variant.
  • Smaller diameter POF (200 µm) yielded superior detection performance compared to larger diameters (500 µm).
  • The developed system and prototype achieved COVID-19 variant detection in under 15 minutes.

Conclusions:

  • The proposed POF U-shaped probe sensing method offers a rapid, sensitive, and portable solution for COVID-19 diagnosis.
  • This technology has the potential to significantly improve clinical diagnostics by reducing time and cost.
  • The approach is particularly beneficial for deployment in remote or underserved areas lacking traditional laboratory facilities.