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Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
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Intimate Relationships and Stroke: Piloting a Dyadic Intervention to Improve Depression
Alexandra L Terrill1, Maija Reblin2, Justin J MacKenzie3
1Department of Occupational & Recreational Therapies, University of Utah, Salt Lake City, UT 84108, USA.
International Journal of Environmental Research and Public Health
|February 15, 2022
Summary
A new remote intervention (ReStoreD) showed promise for reducing depressive symptoms in stroke survivors and partners with severe depression. Further research is needed to confirm its effectiveness.
Area of Science:
- Neurology
- Psychiatry
- Rehabilitation Medicine
Background:
- Post-stroke depression is prevalent in both survivors and partners, negatively impacting quality of life.
- Limited effective interventions exist for managing dyadic post-stroke depressive symptoms.
Purpose of the Study:
- To pilot test a novel, remotely administered 8-week dyadic intervention (ReStoreD).
- To assess the intervention's feasibility and preliminary effects on depressive symptoms in stroke survivor-partner dyads.
Main Methods:
- Thirty-four dyads (stroke survivor and partner) enrolled at least 3 months post-stroke.
- Depressive symptoms were measured pre-intervention, post-intervention, and at 3-month follow-up.
- Repeated measures ANOVA analyzed changes in depressive symptoms over time.
Main Results:
- Twenty-six dyads completed the study.
- A large effect size indicated improvement in depressive symptoms for stroke survivors.
- Partners showed no significant improvement; individuals with higher baseline depression benefited most.
Conclusions:
- The ReStoreD intervention demonstrated proof-of-concept for reducing depressive symptoms, particularly in those with more severe baseline symptoms.
- Future large-scale studies are warranted to establish the intervention's efficacy.
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