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Lyme disease: a review.
Bulletin De La Societe De Pathologie Exotique Et De Ses Filiales
|January 1, 1986
Summary
Lyme disease, caused by Borrelia burgdorferi, presents diverse symptoms, including a characteristic rash and later neurological or joint issues. Diagnostic tests and treatments like penicillin are now available.
Area of Science:
- Infectious Diseases
- Microbiology
- Rheumatology
Background:
- Lyme disease is caused by the spirochete Borrelia burgdorferi.
- The disease has been identified across three continents.
- Clinical presentations of Lyme disease are highly variable.
Purpose of the Study:
- To describe the protean manifestations of Lyme disease.
- To highlight the diagnostic advancements and therapeutic options for Lyme disease.
Main Methods:
- Review of clinical features, including erythema chronicum migrans, meningopolyneuritis, and arthritis.
- Discussion of diagnostic laboratory tests for antibody detection.
- Identification of preferred therapeutic agents.
Main Results:
- Borrelia burgdorferi is the causative agent of Lyme disease.
- Erythema chronicum migrans is the initial hallmark symptom.
- Later manifestations include neurological and arthritic conditions.
- Diagnostic tests show high sensitivity in later disease stages.
- Penicillin and tetracycline are effective treatments.
Conclusions:
- Lyme disease exhibits a wide spectrum of clinical manifestations.
- Accurate diagnostic tests are available, particularly for later stages.
- Effective antibiotic treatments, including penicillin and tetracycline, are established.