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Delamination and dissection of arteriovenous grafts: A multicenter report of four cases
1Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Insights
Graft delamination and dissection are rare causes of arteriovenous (AV) graft failure in hemodialysis patients. These conditions can be successfully treated with interventions like stenting or graft replacement.
Area of Science:
- Vascular Surgery
- Nephrology
- Medical Imaging
Background:
- Arteriovenous (AV) grafts are essential for chronic hemodialysis access.
- Common causes of AV graft failure include stenosis in the artery, graft, or draining vein.
- Rare complications like graft delamination and dissection can also lead to AV graft dysfunction.
Observation:
- Four cases of AV graft dysfunction and failure due to graft delamination and dissection are presented.
- Ultrasound identified delamination and dissection in Acuseal AV grafts between 1 and 33 months post-implantation.
- Patient demographics included two males and two females aged 47-67 years undergoing chronic hemodialysis.
Findings:
- Two patients were successfully treated with stenting and partial graft replacement.
- Fluid withdrawal to reduce false lumen volume was ineffective in one case.
- One instance of delamination and dissection resolved spontaneously after five months.
Implications:
- Graft delamination and dissection should be recognized as a potential cause of AV graft failure.
- Interventional strategies such as stenting and graft replacement may be effective treatments.
- Further research into the mechanisms and optimal management of graft delamination is warranted.
Abstract:
Arteriovenous (AV) grafts are an alternative vascular access for chronic hemodialysis. AV graft failure is often due to stenosis of the feeding artery, graft, or draining vein. We report four cases of AV graft dysfunction and failure rarely caused by graft delamination and dissection. Two males and two females aged 47-67 years had been on chronic hemodialysis. Ultrasound examination detected graft delamination and dissection between 1 and 33 months after Acuseal AV graft implantation. Two cases were successfully treated with stenting and partial graft replacement, respectively. False lumen volume reduction by fluid withdrawal failed to salvage the delaminated graft in one of the patients. The delamination and dissection of another case spontaneously resolved 5 months later. Graft delamination and dissection should be considered as a possible cause for AV graft dysfunction and failure. Stenting and graft replacement may be recommended to treat AV graft dissection and delamination.
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