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Published on: February 7, 2014
Correlation between short-term blood pressure variability parameters with mobil-O-graph pulse wave velocity
Marco Antonio Vieira Silva1,2, Luiz Antonio Pertilli Rodrigues Resende3,4, Mateus Marchiori Vieira5
1Division of Tropical Medicine and Infectious Diseases, Department of Internal Medicine, Federal University of the Triângulo Mineiro, 544 Square, Postal Code, Uberaba, 38025-050, Brazil. marcovieiravs@gmail.com.
Insights
Blood pressure variability (BPV) correlates with arterial stiffness, measured by Mobil-O-Graph pulse wave velocity (PWV). Higher systolic BPV showed a stronger association with increased PWV in suspected hypertensive and treated individuals.
Area of Science:
- Cardiovascular Research
- Hypertension Studies
- Biomedical Engineering
Background:
- Blood pressure variability (BPV) and arterial stiffness are linked to cardiovascular events.
- Previous research indicates a connection between short-term BPV and arterial stiffness.
- No studies have yet explored the correlation between BPV and arterial stiffness using the Mobil-O-Graph device.
Purpose of the Study:
- To investigate the relationship between short-term BPV parameters and Mobil-O-Graph pulse wave velocity (PWV).
- To assess this correlation in individuals with suspected hypertension and those already undergoing treatment.
Main Methods:
- Arterial stiffness was measured using oscillometric PWV (oPWV) via the Mobil-O-Graph device in 649 individuals.
- 24-hour ambulatory blood pressure monitoring was conducted.
- Correlations were analyzed between oPWV and various BPV measures, including 24-h SD, daytime-SD, nighttime-SD, weighted SD (wSD), coefficient of variation (CV 24-h), and average real variability (ARV).
Main Results:
- A positive correlation was observed between oPWV and all systolic BPV measures in both suspected hypertensive and treated groups.
- Systolic daytime-SD and diastolic CV 24-h independently predicted oPWV in the suspected hypertensive and treated groups, respectively.
- Diastolic BPV also showed associations with certain BPV measures, particularly in the treated group.
Conclusions:
- A significant positive and independent correlation exists between Mobil-O-Graph PWV and BPV measures.
- The correlation is stronger for systolic BPV compared to diastolic BPV.
- These findings highlight the clinical relevance of assessing BPV in conjunction with arterial stiffness.
Background:
Blood pressure variability (BPV) and arterial stiffness show an association with increased cardiovascular events. Evidences demonstrated an association between higher short-term systolic BPV and stiffer arteries. There is no previous study assessed the correlation between BPV and arterial stiffness measured by a Mobil-O-Graph device. We issued to evaluate the correlation between short-term BPV parameters and Mobil-O-Graph pulse wave velocity (PWV) among suspected hypertensive individuals under treatment.
Methods:
Mobil-O-Graph device estimated arterial stiffness (oscillometric PWV [oPWV]) in 649 individuals, and they recorded 24-h ambulatory BP; 428 had suspected hypertension and 221 under treatment. We analyzed the correlation between oPWV and measures of BPV: SD of 24 h BP (24-h SD), SD of daytime BP (daytime-SD), and SD of nighttime BP (nighttime-SD), weighted SD of 24-h BP (wSD), coefficient of variation of 24-h BP (CV 24-h) and average real variability (ARV).
Results:
Oscillometric PWV showed a positive correlation with all systolic BPV measures, in both groups. Among suspected hypertensives: 24-h SD, r = 0.30; SD daytime-SD, r = 0.34; nighttime-SD, r = 0.16; wSD, r = 0.30; CV 24-h, r = 0.24; ARV, r = 0.22. In the treated individuals: 24-h SD, r = 0.46; daytime-SD, r = 0.47; nighttime-SD, r = 0.35; wSD, r = 0.50; CV 24-h, r = 0.43; ARV, r = 0.37, all P < 0.001. Diastolic BPV demonstrated association with some measures of BPV. In suspected hypertensive group: nighttime-SD, r = 0.13; wSD, r = 0.10, both P < 0.001. And in treated individuals: daytime-SD, r = 0.23; wSD, r = 0.22; CV 24-h, r = 0.19 (all P < 0.001), ARV, r = 0.15 (P < 0.05). Systolic daytime-SD in suspected and diastolic CV 24-h in treated group independently predicted oPWV.
Conclusion:
We observed a positive and independent correlation between Mobil-O-Graph pulse wave velocity and BPV measures, strong to systolic BPV and weak to diastolic BP.
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