Related Experiment Video
Updated: Oct 3, 2025

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
Published on: May 26, 2023
Cardiopulmonary Arrest After COVID-19 Vaccination: A Case Report
Waleed Sadiq1, Madeeha Subhan Waleed2, Phyllis Suen3
1Medicine, Staten Island University Hospital, New York, USA.
Insights
A rare case of cardiopulmonary arrest occurred after a COVID-19 mRNA booster vaccine in a 59-year-old male. This highlights the need for continued monitoring of vaccine side effects.
Area of Science:
- Cardiology
- Vaccinology
- Public Health
Background:
- Global vaccination efforts aim to mitigate COVID-19 morbidity and mortality.
- mRNA vaccines are a key tool in controlling the pandemic.
- Previous studies have noted associations between mRNA COVID-19 vaccines and myocarditis.
Observation:
- A 59-year-old male experienced cardiopulmonary arrest following an mRNA COVID-19 booster vaccination.
- The patient had no prior history of cardiopulmonary disease.
Findings:
- This case represents the first reported instance of cardiopulmonary arrest occurring after a COVID-19 mRNA booster vaccination.
- The temporal association between the vaccination and the adverse event warrants further investigation.
Implications:
- Further research and case reporting are crucial to confirm a potential causal link.
- Vigilant monitoring of vaccination-associated adverse events is essential.
- Understanding such events is important to address vaccine hesitancy and maintain public trust.
Abstract:
Coronavirus disease 2019 (COVID-19) emerged in Wuhan in 2019 and by far has affected the whole world, and many people have succumbed to the disease. Vaccination programs introduced around the globe are aiming to reduce morbidity, mortality, and disease spread. We report the case of a 59-year-old male who suffered from cardiopulmonary arrest post-COVID-19 mRNA booster vaccination with no history of any other cardiopulmonary disease. Association between myocarditis and mRNA COVID-19 vaccines have been previously reported. However, this is the first case of cardiopulmonary arrest post-COVID-19 booster vaccination. Further research and cases should be described to confirm if this relationship exists. We need further cases to find this temporal association as such cases can also increase vaccine hesitancy. However, vaccination-associated adverse events should be vigilantly monitored and evaluated from time to time as further reports emerge.

