Successful thrombectomy in a pediatric patient with large vessel occlusion and COVID-19 related multisystem...

Area of Science:

• Pediatric Neurology
• Interventional Cardiology
• Infectious Diseases

Background:

• Multisystem inflammatory syndrome in children (MIS-C) is a rare but serious condition associated with COVID-19.
• Acute ischemic stroke is a potential neurological complication of MIS-C.
• Mechanical thrombectomy is an established treatment for acute ischemic stroke in adults, but its use in pediatric MIS-C is not well-documented.

Observation:

• A pediatric patient with MIS-C presented with an acute ischemic stroke involving the right M1 cerebral artery and a large penumbra.
• The patient underwent successful mechanical thrombectomy, achieving TICI 3 recanalization.
• No procedural complications were observed.

Findings:

• The mechanical thrombectomy resulted in significant neurological recovery, with the pediatric National Institutes of Health Stroke Scale (NIHSS) score improving from 16 to 3.
• This case represents the first reported instance of successful mechanical thrombectomy in a pediatric patient with MIS-C associated with COVID-19.

Implications:

• Mechanical thrombectomy can be a safe and effective treatment for acute ischemic stroke in pediatric patients with MIS-C.
• This successful intervention expands treatment options for severe neurological complications of MIS-C.
• Further research is warranted to establish guidelines for mechanical thrombectomy in pediatric MIS-C stroke cases.