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Related Concept Videos

Knee Joint01:23

Knee Joint

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The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
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Cemented Versus Noncemented Total Knee Arthroplasty Outcomes.

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  • 1From the Department of Orthopaedic Surgery, University of California Los Angeles, Los Angeles, CA (Stavrakis, Arshi, Chiou, and Hsiue), the Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA (Horneff), the Department of Orthopaedic Surgery, Cedars-Sinai Kerlan-Jobe Institute, Los Angeles, CA (Photopoulos).

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Noncemented total knee arthroplasty (TKA) shows higher risks of infection and fracture, with no difference in aseptic loosening compared to cemented TKA. Further research is needed on long-term aseptic loosening rates.

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Area of Science:

  • Orthopedic surgery
  • Biomaterials science
  • Medical device engineering

Background:

  • Aseptic loosening is a primary cause for revision total knee arthroplasty (TKA).
  • Younger, active patient demographics prompt reevaluation of noncemented fixation for TKA.
  • Noncemented fixation may offer lower long-term aseptic loosening rates.

Purpose of the Study:

  • To compare demographics and complication rates between cemented and noncemented TKA.
  • To evaluate the risk-adjusted complication profiles of cemented versus noncemented TKA.
  • To analyze outcomes at 90 days, 1 year, and 2 years post-surgery.

Main Methods:

  • Utilized the MKnee database subset for patient identification.
  • Included patients undergoing TKA for osteoarthritis with a minimum 2-year follow-up.
  • Employed propensity score matching for risk-adjusted complication analysis.

Main Results:

  • Noncemented TKA was linked to increased periprosthetic joint infection risk (ORs 1.34-1.27).
  • Noncemented TKA demonstrated higher periprosthetic fracture risk at 1 and 2 years (ORs 2.19, 1.89).
  • No significant difference in aseptic loosening rates was observed between cemented and noncemented TKA.

Conclusions:

  • Noncemented TKA is associated with elevated rates of periprosthetic joint infection and fracture.
  • Long-term aseptic loosening rates require further investigation for both fixation methods.
  • Current evidence does not support noncemented TKA over cemented TKA for reducing aseptic loosening.