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Updated: Oct 3, 2025

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
Published on: April 13, 2022
Effect of chitosan grafting oxidized bacterial cellulose on dispersion stability and modulability of biodegradable
Xiaoli Liu1, Yixin Xu2, Caoyu Guo2
1School of Food Science and Technology, State Key Laboratory of Food Science and Technology, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, Lihu Road 1800, Wuxi, Jiangsu 214122, PR China; Wuqiong Foods Co. , Ltd, Chaozhou, Guangdong 515700, PR China.
Abstract:
Bacterial cellulose (BC) is a kind of high-purity cellulose biomaterial with a unique three-dimensional structure. To improve the mechanical properties and reinforce the BC composite films, in this study, we provide in detail a simple, fast, and environmentally-friendly method to prepare a biodegradable composite film using chitosan (CS) with different molecular weights and BC with excellent dispersion. The water moisture content (MC), water solubility (WS), contact angle (CA), mechanical properties and barrier properties were measured to assess the effect of CSn-OBC composite films. The morphology, structural and thermal properties of the films were evaluated by scanning electron microscopy, spectral analysis, thermogravimetry and X-ray diffraction. Results showed that the biodegradable film prepared by grafting chitosan with high molecular weight and uniformly dispersing bacterial cellulose exhibited superior mechanical properties, water resistance, and thermal stability, which are essential characteristics for commercial applications in complex environments.

