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Updated: Oct 3, 2025

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
Published on: January 24, 2018
Total and partial knee arthroplasty implants that maintain native load transfer in the tibia.
Maxwell J Munford1, Jennifer C Stoddart1, Alexander D Liddle2
1The Biomechanics Group, Department of Mechanical Engineering, Imperial College London, London, UK.
Titanium lattice knee implants successfully restored natural bone stress after unicompartmental and total knee arthroplasty. Conventional implants caused significant underloading, highlighting the potential of lattice designs for improved bone health and implant revision.
Area of Science:
- Biomaterials engineering
- Orthopedic biomechanics
- Surgical innovation
Background:
- Knee replacement surgeries like unicompartmental (UKA) and total knee arthroplasty (TKA) are effective for osteoarthritis.
- However, traditional solid metal implants can alter natural bone stress distribution, potentially leading to bone loss and revision complications.
Purpose of the Study:
- To investigate if titanium lattice UKA and TKA implants can preserve natural load transfer in the proximal tibia.
- To compare the mechanical environment created by lattice implants versus conventional solid implants.
Main Methods:
- Cadaveric knee specimens (n=8) underwent UKA and TKA with both conventional solid and titanium lattice tibial implants.
- Bone-implant interface stress was measured and compared to the native, pre-operative state.
Main Results:
- Titanium lattice implants effectively replicated the native tibia's mechanical environment for both UKA and TKA.
- Conventional solid implants significantly reduced bone stress (by 10x) and caused substantial underloading (>70% of bone surface).
Conclusions:
- Titanium lattice implants maintain natural tibial loading post-arthroplasty, unlike conventional solid implants.
- This represents a promising advancement for preserving bone health, though further evaluation of fatigue and micromotion is necessary for clinical application.
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