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Updated: Oct 3, 2025

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis
Published on: January 26, 2024
Unconventional roles of lactate along the tumor and immune landscape
Luigi Ippolito1, Pierre Sonveaux2, Paola Chiarugi3
1Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Abstract:
The tumor ecosystem evolves with dynamic interactions between cancer and normal cells, and nutrients have emerged as new regulators of cancer hallmarks. Lactate has climbed the rankings as a multifunctional molecule orchestrating many aspects of the disease onset and progression. Here, we patchwork and discuss the main recent findings conferred during the EMBO workshop titled 'Lactate: Unconventional Roles of a Nutrient Along the Tumor Landscape.'
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