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Ischemic Vasculitis as a Cause of Brain Disorder's in Patients with Long Covid: Case Report

Nizama Salihefendic1, Muharem Zildzic2, Haris Huseinagic3

  • 1Polyclinic Medicus "A" Gracanica, Gracanica, Bosnia and Herzegovina.

Medical Archives (Sarajevo, Bosnia and Herzegovina)
|February 16, 2022
PubMed

Insights

Long COVID-19 syndrome can cause neuropsychiatric symptoms in young adults, including brain disorders. Two cases revealed ischemic vasculitis on CT scans, improving with neurological therapy.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Neuroscience

Background:

  • The SARS-CoV-2 pandemic has led to widespread health and socio-economic challenges.
  • COVID-19 can cause persistent symptoms affecting multiple organ systems, including the nervous system.
  • Approximately one-third of patients experience neuropsychiatric symptoms during or after acute infection.

Observation:

  • This report details two young adult females who developed neurological disorders post-COVID-19.
  • Symptoms manifested 1-2 months after acute SARS-CoV-2 infection, without prior respiratory issues.
  • Brain imaging (CT and angiography) revealed signs consistent with ischemic vasculitis in both patients.

Findings:

  • Neuropsychiatric disorders are a common and varied manifestation of Long COVID-19 syndrome.
  • Ischemic vasculitis was identified as a potential cause of neurological symptoms in these young adults.
  • Neurological treatment led to the improvement of observed neuropsychiatric symptoms.

Implications:

  • These cases highlight the diverse neurological complications of Long COVID-19 in younger populations.
  • Early diagnosis and intervention for post-COVID-19 neurological issues, such as ischemic vasculitis, are crucial.
  • Further research is needed to understand the mechanisms and long-term effects of COVID-19 on the brain.
Abstract

Keywords:
COVID-19Ischemic VasculitisLong Covidbrain damageneurological disorders

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