Related Experiment Video
Updated: Oct 3, 2025

05:20
A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
Published on: November 12, 2020
7.7K
Cavernous sinus thrombosis with bilateral orbital vein involvement and diffuse ischemic retinopathy
Diana H Kim1, Sana A Bautista1, Sonul Mehta1
1Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA, USA.
Arquivos Brasileiros De Oftalmologia
|February 16, 2022
Summary
Septic cavernous sinus thrombosis caused vision loss and retinal ischemia. Despite treatment, the patient experienced permanent vision loss in the affected eye.
Area of Science:
- Ophthalmology
- Neurology
- Infectious Diseases
Background:
- Septic cavernous sinus thrombosis is a rare but serious condition.
- Orbital involvement can lead to significant visual impairment.
Observation:
- A 53-year-old man presented with periorbital swelling and left eye vision loss.
- Examination revealed septic cavernous sinus thrombosis with bilateral orbital vein involvement.
Findings:
- Treatment included canthotomy, pressure-lowering drops, antibiotics, and anticoagulation.
- Optical coherence tomography showed diffuse retinal ischemic destruction.
- Vascular occlusion suggested ophthalmic or ciliary artery involvement, not carotid.
Implications:
- This case highlights the severe ophthalmic complications of cavernous sinus thrombosis.
- Prompt diagnosis and multidisciplinary treatment are crucial.
- Permanent vision loss can occur despite aggressive management.
Related Concept Videos
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
54
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
54
Veins of Head and Neck
3.2K
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
3.2K
Venous Thrombosis I: Introduction
58
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
58
Glaucoma: Overview
945
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
945
Venous Thrombosis III: Interprofessional Care
43
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
43
The Arch of Aorta
1.1K
The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
Encircling the heart, the coronary arteries form a ring-like structure before...
1.1K

