Barrett's mucosa with multiple carcinomas of the esophagus and oral cavity

A 62-year-old man with carcinoma of the tongue had two separate asymptomatic carcinomas of the esophagus, one squamous and the other adenocarcinoma arising from Barrett's mucosa. We review the multicentric origin and synchronous occurrence of tumors in the oropharyngoesophageal area with and without Barrett's mucosa to emphasize the importance of complete evaluation of the esophagus in patients with oropharyngeal malignancy.