Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Human Genetics01:28

Human Genetics

788
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
788
Drug Regulation01:25

Drug Regulation

2.0K
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
2.0K
Clinical Trials: Overview01:11

Clinical Trials: Overview

3.7K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
3.7K
What is Genetic Engineering?00:49

What is Genetic Engineering?

76.0K
Overview
76.0K
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

5.9K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.9K
Ethics in Research01:56

Ethics in Research

24.7K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
24.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Economic Evaluation of Interventions for Children with Neurodevelopmental Disorders: Practical Guidance.

PharmacoEconomics·2026
Same author

Resource Use and Costs of Nurse Navigator Support for Parents of High-Risk Infants After Discharge from a Neonatal Intensive Care Unit.

Children (Basel, Switzerland)·2026
Same author

Understanding the decision of parents to opt-out of medically actionable secondary findings offered through genome sequencing.

Journal of genetic counseling·2026
Same author

Incorporating Personal Utility in Health Technology Assessment of Emerging Genomic and Genetic Testing Technologies.

The American journal of bioethics : AJOB·2026
Same author

Understanding the impact of genomic secondary findings on clinical care and patient experience: a protocol for a prospective observational study.

BMJ open·2026
Same author

Patient experiences of treatment-resistant depression (TRD): A systematic review and qualitative meta-synthesis.

PLOS mental health·2026

Related Experiment Video

Updated: Oct 3, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

34.1K

Considerations for developing regulations for direct-to-consumer genetic testing: a scoping review using the 3-I

Alexandra Cernat1,2, Naazish S Bashir2, Wendy J Ungar3,4

  • 1Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.

Journal of Community Genetics
|February 16, 2022
PubMed
Summary

Direct-to-consumer (DTC) genetic testing needs regulation. This study analyzes ethical, legal, and social issues to inform policy development for safer genetic testing practices.

Keywords:
Direct-to-consumer screening and testingGenetic testingHealth policyHealth services researchReview

More Related Videos

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.3K
Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.2K

Related Experiment Videos

Last Updated: Oct 3, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

34.1K
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.3K
Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.2K

Area of Science:

  • Genetics
  • Bioethics
  • Health Policy

Background:

  • Direct-to-consumer (DTC) genetic testing operates with minimal regulatory oversight.
  • Comprehensive analyses of ethical, social, legal, and technological aspects for DTC genetic testing regulation are scarce.

Purpose of the Study:

  • To analyze the ideas, interests, and institutions relevant to policy development for DTC genetic testing.
  • To provide a framework for understanding and addressing the regulatory gaps in DTC genetic testing.

Main Methods:

  • A scoping review of 99 publications, reports, governmental documents, and legislation was conducted.
  • The 3-I policy analysis framework (Ideas, Interests, Institutions) was employed.
  • Searched citation databases for implications, stakeholder perspectives, and healthcare system effects of DTC genetic testing.

Main Results:

  • Key ideas include autonomy, informed decision-making, privacy, clinical validity, and utility.
  • Interests of the public and healthcare providers were examined.
  • Relevant institutions include regulatory bodies (e.g., FDA), genetic testing laws, and anti-discrimination legislation.

Conclusions:

  • Policy makers can use this analysis to develop or enhance DTC genetic testing regulations.
  • Recommendations include assessing clinical validity, controlling marketing, and ensuring healthcare provider involvement and informed consent.