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Updated: Oct 3, 2025

Analysis of Beta-cell Function Using Single-cell Resolution Calcium Imaging in Zebrafish Islets

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Imaging β-Cell Function Using a Zinc-Responsive MRI Contrast Agent May Identify First Responder Islets.

Bibek Thapa¹, Eul Hyun Suh¹, Daniel Parrott^1,2

¹Advanced Imaging Research Center, The University of Texas Southwestern Medical Center, Dallas, TX, United States.

Frontiers in Endocrinology

|February 17, 2022

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This study introduces a novel MRI method to visualize real-time beta-cell function in rats. The technique detects glucose-stimulated insulin and zinc secretion, identifying distinct islet responses and aiding diabetes research.

Failed At:

2026-06-19T13:48:38.545912+00:00

Keywords:

glucose stimulated zinc secretion (GSZS)glucose-stimulated insulin secretion (GSIS)magnetic resonance imaging metabolic imaging pancreatic β-cell function zinc-responsive contrast agent

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