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Related Concept Videos

Plant Breeding and Biotechnology01:59

Plant Breeding and Biotechnology

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Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
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Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
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The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
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Related Experiment Video

Updated: Oct 3, 2025

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
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Crop Quality Improvement Through Genome Editing Strategy.

Yihao Yang1,2,3, Chenda Xu1,2, Ziyan Shen1,2

  • 1Jiangsu Key Laboratory of Crop Genetics and Physiology/Key Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding, Yangzhou, China.

Frontiers in Genome Editing
|February 17, 2022
PubMed
Summary

CRISPR/Cas9 genome editing efficiently improves crop quality by modifying genes. This review covers its applications in enhancing nutrients and reducing anti-nutritional factors, offering future perspectives.

Keywords:
CRISPR/Cas9cropgene editingimprovementquality

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Area of Science:

  • Agricultural Science
  • Genetics
  • Biotechnology

Background:

  • Crop quality is crucial for breeders and consumers but is a complex trait difficult to improve using traditional methods.
  • Environmental and genetic factors significantly influence crop quality, posing challenges for selective breeding.
  • The CRISPR/Cas9 system offers precise genome editing capabilities, revolutionizing crop improvement.

Purpose of the Study:

  • To review the genome editing capabilities of CRISPR/Cas9 for crop quality enhancement.
  • To highlight advances in improving crop quality aspects like nutrients and anti-nutritional factors.
  • To discuss challenges and future directions for genome editing in agriculture.

Main Methods:

  • Review of CRISPR/Cas9 genome editing techniques including gene knockout, knock-in, base editing, prime editing, and gene expression regulation.
  • Analysis of studies applying CRISPR/Cas9 for crop quality improvement.
  • Discussion of challenges and future perspectives in the field.

Main Results:

  • CRISPR/Cas9 enables diverse genome modifications for crop improvement.
  • Significant progress has been made in enhancing macronutrients, micronutrients, and reducing anti-nutritional factors in crops.
  • The system offers targeted approaches to complex trait improvement.

Conclusions:

  • CRISPR/Cas9 is a powerful tool for improving crop quality traits.
  • Further research and application of genome editing hold great promise for sustainable agriculture.
  • Addressing challenges will be key to fully realizing the potential of this technology.