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Draft Genome Sequence of Bacteriocin-Encoding Enterococcus faecium Strain S6, Isolated from Camel Milk
Abrar Akbar1, Rita Rahmeh1, Mohamad Kishk1
1Kuwait Institute for Scientific Research, Safat, Kuwait.
Microbiology Resource Announcements
|February 17, 2022
Summary
A novel bacteriocin-producing bacterium, Enterococcus faecium strain S6, was identified in raw camel milk. Its genome sequencing revealed genetic insights into its antimicrobial capabilities, offering potential for new applications.
Area of Science:
- Microbiology
- Genomics
- Food Science
Background:
- Bacteriocins are antimicrobial peptides with therapeutic and food preservation potential.
- Enterococcus faecium is a species known for producing various bioactive compounds.
- Raw camel milk is an under-explored source of novel microorganisms.
Purpose of the Study:
- To identify and characterize a novel bacteriocin-producing Enterococcus faecium strain from raw camel milk.
- To perform whole-genome sequencing of the identified strain.
- To analyze the genome for genes related to antimicrobial production and properties.
Main Methods:
- Isolation and identification of Enterococcus faecium strain S6 from raw camel milk.
- Whole-genome sequencing using next-generation sequencing technologies.
- Bioinformatic analysis of the draft genome sequence to identify coding genes and functional elements.
Main Results:
- Enterococcus faecium strain S6 was successfully isolated and identified.
- The draft genome sequence comprises 2,617,971 base pairs with a G+C content of 37.99%.
- The genome contains 2,407 predicted coding genes, including those potentially involved in bacteriocin synthesis and antimicrobial activity.
Conclusions:
- The genome sequence of Enterococcus faecium strain S6 provides a valuable resource for understanding its antimicrobial mechanisms.
- Strain S6 represents a promising candidate for developing novel antimicrobial agents derived from a natural source.
- Further research can explore the application of strain S6 and its bacteriocins in food safety and therapeutics.

