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Updated: Oct 3, 2025

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
Published on: March 12, 2016
[Neuropsychological disorders in patients with glaucoma]
A N Bogolepova1,2, E V Makhnovich1,2, A N Jyravleva3
1Pirogov Russian National Research Medical University, Moscow, Russia.
Objective:
To compare the structure of cognitive deficit in patients with glaucoma, Alzheimer's disease (AD) and vascular dementia (VD).
Material And Methods:
Ninety patients were comprehensively examined and divided into 3 groups of 30 people each: AD group, VD group and open-angle glaucoma group. All patients underwent neurological and neuropsychological examination.
Results:
The data on the similarity of the structure of cognitive deficit in patients with AD and glaucoma were obtained. More than half of patients with open-angle glaucoma were newly diagnosed with moderate cognitive impairment.
Conclusion:
The results indicate the need for a comprehensive neurological and neuropsychological examination of patients with glaucoma for the early diagnosis of cognitive disorders, timely therapy and an improvement in the prognosis of the disease.
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