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Updated: Oct 3, 2025

Establishing a Competing Risk Regression Nomogram Model for Survival Data
Published on: October 23, 2020
Two-sample survival probability curves: A graphical approach for the analysis of time to event data in clinical
Sandra Castro-Pearson1, Chap T Le2, Xianghua Luo2
1Division of Biostatistics, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA.
Abstract:
With the aim to improve the communication of trial results, we introduce a novel graphical approach that complements the analysis of time to event outcomes in two-arm randomized trials. We define the so-called two-sample survival probability curve and propose a nonparametric estimator of the curve based on a random walk using Kaplan-Meier survival estimates for the two arms. We then use the estimated curve to visualize treatment effect as well as potential effect modification of factors of interest. We also propose to estimate two-sample survival probability curves within the framework of the Cox model to graphically assess model fit. The proposed two-sample survival probability plot puts trials in a standardized [0,1] × [0,1] space, allowing for a simple visualization of the main effect, effect modification, and the adequacy of a model fit.
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