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Updated: Oct 3, 2025

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
Published on: January 5, 2018
Brief intervention for hazardous drinking delivered using text messaging: a pilot randomised controlled trial from
Abhijit Nadkarni1,2, Danielle Fernandes2, Urvita Bhatia2
1Centre for Global Mental Health, London School of Hygiene & Tropical Medicine, London, UK.
Objective:
To evaluate the feasibility and acceptability of a mobile-based brief intervention (BI), generate preliminary estimates of the impact of the BI and fine-tune the procedures for a definitive randomised controlled trial.
Design:
Parallel three-arm single-blind individually randomised controlled pilot trial. Eligible and consenting participants were randomised to receive mobile-based BI, face-to-face BI and information leaflet.
Setting:
Educational institutions, workplaces and primary care centres.
Participants:
Adult hazardous drinkers.
Results:
Seventy-four participants were randomised into the three trial arms; forty-eight (64·9 %) completed outcome evaluation. There were no significant differences between the three arms on change in any of the drinking outcomes. There were however in two-way comparisons. Face-to-face BI and mobile BI were superior to active control for percent days heavy drinking at follow-up, and mobile BI was superior to active control for mean grams ethanol consumed per week at follow-up.
Conclusion:
The encouraging findings about feasibility and preliminary impact warrant a definitive trial of our intervention and if found to be effective, our intervention could be a potentially scalable first-line response to hazardous drinking in low-resource settings.
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