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Updated: Oct 3, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Modulation of the gut microbiota: opportunities and regulatory aspects
Davide G Ribaldone1, Rinaldo Pellicano2, Sharmila Fagoonee3
1Department of Surgical Sciences, University of Turin, Turin, Italy - davrib_1998@yahoo.com.
Abstract:
The human gut is an intensively colonized organ containing microorganisms that can be health-promoting or pathogenic. This feature led to the development of functional foods aiming to fortify the former category at the expense of the latter. Since long, cultured products, including probiotics fortification, have been used for humans as live microbial feed additions. This review presents some of the microbes used as probiotics and discusses how supplementation with probiotics may help initiate and/or restore eubiotic composition of gut microbiota. Additionally, it considers safety and regulatory aspects of probiotics.
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