Functionality-driven food product formulation - An illustration on selecting sustainable ingredients building

Anouk Lie-Piang1, Anna Cäcilie Möller1, Nienke Köllmann1

  • 1Food Process Engineering Group, Wageningen University, PO Box 8129, 6700 EV Wageningen, the Netherlands.

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Orally administered drugs primarily enter the systemic circulation via passive diffusion through the intestinal membranes. The drug's absorption is influenced by drug stability in the gastrointestinal GI tract, membrane permeability, the surface area available for absorption, luminal drug concentration, and residence time in the lumen. Drug permeability can be enhanced by adjusting the lipophilicity, polarity, or molecular size of the drug, promoting its passive transport across intestinal...
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Factors Influencing Drug Absorption: Pharmaceutical Parameters01:28

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Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
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Factors Affecting Workability01:24

Factors Affecting Workability

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Design Example: Deciding Thickness of Lubricating Fluid in a Shaft01:23

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Factors Influencing Drug Absorption: Physicochemical Parameters01:22

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Viscosity01:17

Viscosity

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