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Prevalence and risk factors of discomfort in infants with severe bronchiolitis

Justine Leboucher1, Christophe Milési2, Alice Fumagalli1

  • 1Pediatric Intensive Care Unit, Grenoble-Alpes University Hospital, Grenoble, France.

Acta Paediatrica (Oslo, Norway : 1992)
|February 19, 2022
PubMed

Insights

Infants with severe bronchiolitis on noninvasive ventilation experienced low discomfort. Bilevel positive airway pressure (BiPAP) was associated with slightly higher discomfort scores in these infants.

Area of Science:

  • Pediatric critical care
  • Neonatology
  • Respiratory medicine

Background:

  • Severe bronchiolitis is a common respiratory illness in infants.
  • Noninvasive ventilation (NIV) is frequently used to support infants with respiratory distress.
  • Assessing discomfort in infants receiving NIV is crucial for optimizing care.

Purpose of the Study:

  • To determine the prevalence of discomfort in infants with severe bronchiolitis receiving NIV.
  • To identify potential risk factors for discomfort in this population.

Main Methods:

  • A single-center retrospective observational study.
  • Discomfort was measured using the EDIN (Echelle de Douleur et d'Inconfort du Nouveau-né) scale.
  • Ninety-one infants were included in the analysis.

Main Results:

  • Overall, infants showed low mean EDIN scores (<8) during the first three ICU days.
  • Infants receiving bilevel positive airway pressure (BiPAP) had significantly higher EDIN scores on Days 1 and 2 compared to other NIV methods (p < 0.001).
  • No correlation was found between discomfort levels and the degree of respiratory distress.

Conclusions:

  • Infants with severe bronchiolitis on NIV experience minimal discomfort in the initial ICU period.
  • BiPAP may be associated with a higher degree of discomfort compared to other NIV strategies.
  • Discomfort levels are not directly correlated with respiratory distress severity in this cohort.
Abstract

Keywords:
acute respiratory failurebronchiolitisdiscomfortintensive care unitpain

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