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Updated: Oct 3, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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Published on: February 9, 2021

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Expanding the structure-activity relationship of cytotoxic diphenyl macrocycles

Alejandra Chávez-Riveros1, Ángel Ramírez-Trinidad2, Eduardo Hernández-Vázquez2

  • 1Department of Organic Chemistry, Chemistry Institute, UNAM, Circuito exterior S.N., Ciudad Universitaria, Coyoacán, México DF 04510, Mexico; Universidad Tecnológica de México-UNITEC MÉXICO - Campus Marina-Cuitláhuac, Norte 67 No. 2346, San Salvador Xochimanca, Azcapotzalco, DF 02870, Mexico.

Bioorganic & Medicinal Chemistry Letters
|February 19, 2022
PubMed

Keywords:
Anti-proliferative activityCross-coupling macrocyclizationCytotoxicityMacrocyclesMulticomponent reactions

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