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Related Concept Videos

Clinical Trials: Overview01:11

Clinical Trials: Overview

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Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
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Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
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Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
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Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
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Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
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Digital platforms for clinical trials: The Eureka experience.

Noah D Peyser1, Gregory M Marcus1, Alexis L Beatty2

  • 1Division of Cardiology, University of California, San Francisco, San Francisco, CA, USA.

Contemporary Clinical Trials
|February 20, 2022
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Summary

Digital health research platforms streamline clinical trials. The Eureka platform digitizes health research, enabling remote recruitment and mobile data collection for faster, more efficient studies.

Keywords:
Digital trialsElectronic data captureMobile healthWearable devices

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Area of Science:

  • Health Informatics
  • Clinical Research Methodology
  • Digital Health

Background:

  • Clinical trials are essential for evaluating new health interventions.
  • Digital methods offer potential benefits for clinical research efficiency.
  • Challenges exist in implementing digital approaches in clinical research.

Purpose of the Study:

  • To describe the cumulative experience with the Eureka Research Platform.
  • To highlight the platform's role in digitizing and mobilizing health research.
  • To discuss emerging opportunities in digital clinical research.

Main Methods:

  • The Eureka Research Platform facilitates digital health research.
  • Key features include remote recruitment and mobile data collection.
  • Geofencing and ecological momentary assessments are utilized.

Main Results:

  • The Eureka platform has supported over 50 launched studies.
  • Digital methods enable innovative trial designs and remote strategies.
  • Experience demonstrates the platform's utility in health research.

Conclusions:

  • Digital platforms like Eureka are crucial for advancing clinical research.
  • The platform supports efficient data collection and intervention delivery.
  • Future opportunities exist for further innovation in digital trials.