Related Experiment Video
Updated: Oct 3, 2025

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
Published on: February 16, 2024
Gastric inverted hyperplastic polyp, an exceptional case diagnosed after endoscopic submucosal dissection.
Hoi-Ioi Ng1, Zheng-Qi Li1, Yue-Ming Zhang1
1Department of Endoscopy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Gastric inverted hyperplastic polyps (GIHPs) are rare, growing downward into the submucosa. This case highlights a heart-shaped GIHP successfully removed via endoscopic submucosal dissection, differentiating it from gastritis cystica profunda.
Area of Science:
- Gastroenterology
- Gastrointestinal Pathology
Background:
- Gastric inverted hyperplastic polyps (GIHPs) are uncommon lesions characterized by downward growth into the submucosa.
- Distinguishing GIHPs from other gastric lesions, such as gastritis cystica profunda, is crucial for accurate diagnosis and management.
Observation:
- A rare case of a heart-shaped gastric inverted hyperplastic polyp is presented.
- The polyp exhibited characteristic downward submucosal growth.
Findings:
- The heart-shaped GIHP was successfully removed using endoscopic submucosal dissection (ESD).
- Histopathological examination confirmed the diagnosis and differentiated it from gastritis cystica profunda.
Implications:
- Endoscopic submucosal dissection is a viable treatment option for gastric inverted hyperplastic polyps.
- Accurate differentiation of GIHPs from gastritis cystica profunda is essential to avoid misdiagnosis and ensure appropriate patient care.
More Related Videos
Related Concept Videos
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures III: Video Capsule Endoscopy
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...

