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Published on: February 15, 2018
Effect of an exclusive human milk diet on feeding tolerance in preterm infants
Hiba El-Fadeel1, Pradeep Velumula1, Mirjana Lulic-Botica2
1Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI, 48201, USA.
Objective:
To compare the time to full enteral feeds in preterm infants fed exclusive human milk (EHM) - mother's own milk (MOM) fortified with human milk-based fortifier (HMBF), to those who received partial human milk (PHM) - MOM fortified with bovine milk-based fortifier (BMBF), and exclusive formula.
Study Design:
A single-center retrospective study of infants with birth weight <1250 g from 2013 to 2018. Data on feeding, growth and other short-term neonatal morbidities were collected.
Results:
On regression analysis, time to full enteral feeds was significantly higher in PHM compared to EHM group (β-coefficient 4.14, 95% CI 0.00-8.29) and formula-fed group compared to EHM (β-coefficient 4.3, 95% CI 0.32-8.20). No significant differences in growth velocity, length of stay and other morbidities were found between the groups.
Conclusion:
Infants in EHM had better feeding tolerance and reached their enteral feed goals sooner compared to PHM and formula-fed groups.
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