Biomechanics in Keratoconus Diagnosis

Area of Science:

• Ophthalmology
• Biomedical Engineering
• Medical Imaging

Background:

• Ectatic corneal diseases require accurate assessment for effective management.
• Corneal biomechanics plays a vital role in understanding disease progression.
• Current diagnostic methods may benefit from advanced biomechanical evaluation.

Purpose of the Study:

• To review the significance of biomechanical assessment in ectatic corneal diseases.
• To highlight its role in screening, diagnosis, prognosis, and follow-up.
• To emphasize the integration of biomechanical data for improved clinical outcomes.

Main Methods:

• Prospective review of biomechanical assessment techniques.
• Demonstration of Ocular Response Analyzer (ORA) and Corvis ST for in vivo biomechanics.
• Mention of novel techniques like Brillouin optical microscopy and OCT elastography.

Main Results:

• Biomechanical assessment provides critical data for ectatic corneal diseases.
• Multiple devices and techniques are available for in vivo corneal biomechanical measurement.
• AI integration with multimodal imaging enhances diagnostic accuracy.

Conclusions:

• Biomechanical assessment is indispensable for ectatic corneal diseases.
• Advanced imaging and AI integration offer superior diagnostic capabilities.
• Personalized patient management can be improved through biomechanical insights.