Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Christian Sommer1, Ismail Özden2, Mathias S Weyland1

  • 1ZHAW School of Engineering, 8401 Winterthur, Switzerland.

Zeitschrift Fur Medizinische Physik
|February 21, 2022
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Radiomics-informed CT protocol optimization through feature-level trade-off analysis in a phantom study.

Physics in medicine and biology·2026
Same author

Knowledge preservation in the era of big science and AI: strategies for sustainable scientific research.

Nature communications·2026
Same author

Specialised and persistent raw material procurement by humans in the Middle Pleistocene.

Nature communications·2026
Same author

Climate's firm grip on glacier ablation in the Cordillera Darwin Icefield, Tierra del Fuego.

Nature communications·2025
Same author

Low-dose lung CT: Optimizing diagnostic radiation dose - A phantom study.

European journal of radiology open·2024
Same author

The Use of Survival Dose-Rate Dependencies as Theoretical Discrimination Criteria for <i>In-Silico</i> Dynamic Radiobiological Models.

Dose-response : a publication of International Hormesis Society·2024
Same journal

Can intracochlear voltage matrix analysis explain the occurrence of electrically evoked vestibular responses in cochlear implant users?

Zeitschrift fur medizinische Physik·2026
Same journal

Limitations of Mono-Exponential Individual Fitting as a Reference Model for Single-Time-Point Dosimetry in [<sup>177</sup>Lu]Lu-PSMA-617 Therapy.

Zeitschrift fur medizinische Physik·2026
Same journal

Determination of long-range resistance from high resolution impedance spectroscopy in human cadaveric heads.

Zeitschrift fur medizinische Physik·2026
Same journal

Patient-specific quality assurance in stereotactic radiotherapy: clinical practice in absence of guidelines - status and new approach from the DGMP working group for physics and technology in stereotactic radiotherapy.

Zeitschrift fur medizinische Physik·2026
Same journal

Potential and challenges of Positron Emission Tomography beyond conventional preclinical and clinical imaging.

Zeitschrift fur medizinische Physik·2026
Same journal

Evaluation of PET/CT Artificial Intelligence Image Reconstructions VS Harmonized Clinical Reconstruction.

Zeitschrift fur medizinische Physik·2026
See all related articles

A new phantom and difference detail curve (DDC) method enable CT scan image quality assessment. This approach is effective for evaluating low contrast detectability and inter-observer variability in clinical settings.

Area of Science:

  • Medical Imaging Physics
  • Radiological Sciences
  • Quantitative Imaging

Background:

  • Assessing computed tomography (CT) image quality is crucial for diagnostic accuracy.
  • Existing methods may not adequately capture dose-related image quality, especially in low contrast scenarios.
  • Standardized phantoms and objective metrics are needed for reliable CT performance evaluation.

Purpose of the Study:

  • To introduce and validate a novel measurement method for dose-related CT image quality assessment.
  • To demonstrate the utility of the difference detail curve (DDC) method in a low contrast imaging setting.
  • To quantify inter-observer variability in CT image quality assessment using the proposed method.

Main Methods:

  • Development of a specialized phantom with elliptical slices and insertable contrast modules using resin mixtures with varying CT numbers.
Keywords:
CT image qualityCT phantomDifference detail curveLow contrast CT

Related Experiment Videos

  • Characterization of the phantom for contrast accuracy, energy dependency, and long-term drift.
  • Application of the difference detail curve (DDC) method to analyze 655 CT scans from diverse clinical sites and scanner models, involving human observers and custom software (RadiVates).
  • Main Results:

    • The phantom demonstrated contrast accuracy and energy dependency comparable to water and soft tissue.
    • The DDC method successfully assessed image quality across multiple CT scanners and institutions.
    • Inter-observer variability was quantified and identified as a significant factor in overall measurement variability.

    Conclusions:

    • The developed phantom and DDC method provide a feasible approach for assessing CT image quality, particularly in low contrast conditions.
    • The method allows for objective evaluation of CT scanner performance and understanding of variability sources.
    • This work contributes to standardized and reliable CT image quality assessment in clinical practice.