Related Experiment Video
Updated: Oct 3, 2025

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
Published on: April 7, 2023
Evaluation of Suspected COVID-19 Patients in a Pediatric Emergency Department
Halise Akça1,2, Funda Kurt2, Ayla Akça Çağlar2
1Department of Pediatric Emergency Medicine, Faculty of Medicine, Ankara Yildirim Beyazit University, Ankara, Turkey.
Insights
In a study of 1,812 children, 20.1% tested positive for Coronavirus disease 2019 (COVID-19). Household exposure was common, and lymphopenia was a potential indicator of COVID-19 in pediatric patients.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Coronavirus disease 2019 (COVID-19) became a global pandemic.
- Understanding COVID-19 prevalence and characteristics in children is crucial for public health management.
Purpose of the Study:
- To determine the prevalence of COVID-19 in pediatric patients.
- To compare clinical and laboratory characteristics between COVID-19 positive and negative pediatric patients.
- To identify potential predictors of COVID-19 in children.
Main Methods:
- A retrospective study was conducted from March to May 2020 at a tertiary children's hospital.
- Included were 1,812 patients under 18 years old who underwent SARS-CoV-2 polymerase chain reaction testing.
- Data collected included demographics, symptoms, exposure history, laboratory results, and chest radiography findings.
Main Results:
- Overall, 365 (20.1%) pediatric patients tested positive for COVID-19.
- Positive patients were older and more likely to have had close contact with an infected household member.
- Common symptoms included fever and cough; a higher rate of asymptomatic cases was observed in the positive group.
- Lymphopenia was present in 29.9% of positive children and was associated with lower white blood cell, neutrophil, lymphocyte, and platelet counts, and C-reactive protein levels.
- Chest radiography revealed pathological findings in 29.7% of positive patients.
Conclusions:
- Household exposure is a significant factor in pediatric COVID-19 cases.
- Lymphopenia may serve as a predictive marker for COVID-19 positivity in children.
- Effective management requires heightened awareness, strict infection control, and family-centered health strategies.
Abstract:
Coronavirus disease 2019 (COVID-19) is now a global pandemic. The aim of this study was to investigate the prevalence of COVID-19 in pediatric patients and to compare the characteristics of positive and negative patients. This study conducted from March to May 2020 in a tertiary children's hospital. Patients were included if they were under 18 years old and a SARS-CoV-2 polymerase chain reaction test had been performed. Of the 1,812 patients included in the study, 365 (20.1%) were positive for COVID-19. The median age was 102 months in the positive group, 70 months in the negative group ( p < 0.001). The sex distribution was almost equal. Nearly all positive patients had been in close contact with a COVID-19 infected family household member ( p < 0.001). The most common symptoms were fever (54.4%) and cough (38.6%). The asymptomatic patient rate was higher in the positive group ( p < 0.001). Lymphopenia (<1500/mm 3 ) was found in 29.9% of the positive children ( p = 0.005). When the groups were compared, white blood cell, neutrophil, lymphocyte, and platelet counts; neutrophil-to-lymphocyte ratio; and C-reactive protein level were lower in the positive group. Chest radiography was performed in 95.3% of the positive patients, and the results of 29.7% of them were interpreted as pathological ( p < 0.001). Most of the pediatric patients had a history of contact with COVID-19 positive individuals, and therefore, the diagnosis is generally suspected from a history of household exposure to COVID-19. Lymphopenia can help predict positivity. Awareness, reinforcing infection control measures, and performing health management within families are important steps to manage these patients.
More Related Videos
Related Concept Videos
Assessment of Respiration
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like...
Pneumonia III: Complications and Assessment
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Assessment of apical pulse
Assessing the apical pulse is a critical nursing procedure, particularly indicated for:
Cardiopulmonary Resuscitation III: AED Use

