Related Experiment Video

Updated: Oct 3, 2025

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
15:43

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

23.0K

An Interesting Case of Klebsiella Pneumoniae Pylephlebitis

Sneha Adidam1, Lorenzo Leys2, Siham Mahgoub3

  • 1Internal Medicine, Howard University Hospital, Washington DC, USA.

Cureus
|February 21, 2022
PubMed

Insights

Pylephlebitis, a rare but fatal portal vein thrombophlebitis, is often caused by polymicrobial bacteria. This case highlights a fatal outcome from Klebsiella pneumoniae bacteremia and pylephlebitis despite treatment.

Area of Science:

  • Medical microbiology
  • Vascular medicine
  • Infectious diseases

Background:

  • Pylephlebitis is suppurative thrombophlebitis of the portal venous system, a rare and potentially fatal condition.
  • It is typically caused by polymicrobial bacteria, with Escherichia coli and Streptococcus species being most common.

Observation:

  • This report details a case of a middle-aged female patient diagnosed with Klebsiella pneumoniae bacteremia and pylephlebitis.
  • Portal vein thrombosis was confirmed via abdominal ultrasound.

Findings:

  • Despite treatment with broad-spectrum antibiotics and anticoagulation, the patient experienced multiorgan failure and septic shock.
  • The patient succumbed to complications on the second day of intensive care.

Implications:

  • This case underscores the severe prognosis of Klebsiella pneumoniae-associated pylephlebitis.
  • It highlights the critical need for prompt diagnosis and aggressive management of portal venous system infections.
Keywords:
abdominal painklebsiella pneumoniaeportal vein pylephlebitisportal vein thrombosispylephlebitisseptic portal vein thrombosis

More Related Videos

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii09:17

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

Published on: January 2, 2017

14.8K
Experimental Model to Evaluate Resolution of Pneumonia09:49

Experimental Model to Evaluate Resolution of Pneumonia

Published on: February 17, 2023

1.5K

Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
63
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
509
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
81
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
377
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
883
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
131