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Hepatocellular Carcinoma Complicated by Echinococcal Cyst: A Case Report
Jiwu Guo1,2,3, Chenzhe Ma2,3, Xuewen Song4
1Department of General Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Frontiers in Surgery
|February 21, 2022
Summary
This case highlights the rare co-occurrence of hepatocellular carcinoma (HCC) and hepatic hydatid disease. Management involved surgery, transarterial chemotherapy embolization (TACE), and long-term antiviral and antiparasitic treatment.
Area of Science:
- Hepatology
- Parasitology
- Oncology
Background:
- Hepatocellular carcinoma (HCC) and hepatic hydatid disease are rarely diagnosed together.
- Hepatitis B virus (HBV) infection is a known risk factor for HCC.
- Hydatid disease is caused by Echinococcus infection.
Observation:
- A 54-year-old female with a history of HBV infection presented with abdominal pain.
- Abdominal CT revealed liver lesions suspicious for both HCC and hydatid disease.
- Elevated alpha-fetoprotein (AFP) and positive Casoni test supported the diagnoses.
Findings:
- The patient underwent surgical resection of HCC and hydatid cysts.
- Post-operative treatment included albendazole, entecavir for HBV, and transarterial chemotherapy embolization (TACE).
- Despite rising AFP levels, imaging showed no clear HCC recurrence after treatment.
Implications:
- This case underscores the importance of considering co-infections in liver disease diagnosis.
- Multimodal treatment including surgery, chemotherapy, and antiparasitic/antiviral therapy is crucial.
- Long-term monitoring is essential due to potential AFP elevation without imaging evidence of recurrence.
Keywords:
alpha-fetoproteincase reporthepatic hydatid diseasehepatitis B virushepatocellular carcinomaMore Related Videos
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