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Anterior Segment Optic Coherence Tomography Changes Before and After Phacoemulsification in Primary Open-Angle
Sibel Zirtiloglu1, Ozen Ayranci Osmanbasoglu1, Tulay Alpar Akcetin1
1Department of Ophthalmology, Istanbul Training and Research Hospital, Istanbul, Turkey.
Beyoglu Eye Journal
|February 21, 2022
Summary
Phacoemulsification with intraocular lens implantation widens the anterior chamber angle in primary open-angle glaucoma patients. This surgical intervention leads to reduced intraocular pressure (IOP), improving glaucoma management.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Surgical Innovation
Background:
- Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness.
- Effective management of POAG often requires lowering intraocular pressure (IOP).
- Phacoemulsification with intraocular lens (IOL) implantation is a common cataract surgery that may impact anterior segment parameters.
Purpose of the Study:
- To evaluate the effect of phacoemulsification with IOL implantation on anterior chamber parameters in POAG patients.
- To assess changes in anterior chamber angle (ACA), iris thickness, corneal thickness, and angle-opening distance (AOD).
- To determine the impact of these changes on intraocular pressure (IOP) post-surgery.
Main Methods:
- Anterior segment optical coherence tomography (AS-OCT) was used to measure ocular parameters.
- Data from 49 eyes of 39 POAG patients were analyzed.
- Preoperative and postoperative measurements were compared using statistical tests (paired t-test, Wilcoxon test).
Main Results:
- Corneal thickness showed no significant change post-surgery (p=0.480).
- Significant widening was observed in ACA, AOD, iris curvature, anterior chamber depth, and trabecular-iris space area (p<0.001).
- Intraocular pressure (IOP) significantly decreased at 1 and 3 months post-surgery (p=0.019; p=0.003).
Conclusions:
- Phacoemulsification with IOL implantation effectively increases anterior chamber dimensions in POAG patients.
- The observed anatomical changes correlate with a significant reduction in IOP.
- This surgical approach offers a potential benefit for IOP control in glaucoma management.
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