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A clinical view of clobazam
British Journal of Clinical Pharmacology
|January 1, 1979
Summary
Clobazam (Frisium) is an effective daytime tranquilizer comparable to new benzodiazepines, suitable for various disorders and outpatient treatment due to its safety profile and minimal impact on daily functioning.
Area of Science:
- Pharmacology
- Neurology
Background:
- Clobazam (Frisium) is a benzodiazepine derivative with demonstrated tranquilizing effects.
- Existing literature and new data support its efficacy.
Purpose of the Study:
- To evaluate clobazam as a daytime tranquilizer.
- To assess its suitability for various patient populations and treatment settings.
Main Methods:
- Literature review and presentation of original research results.
- Clinical evaluation of clobazam's efficacy and side-effect profile.
Main Results:
- Clobazam exhibits a tranquilizing profile comparable to newer benzodiazepine derivatives.
- It is indicated for disorders of the sleeping-waking rhythm and psychovegetative disorders in epilepsy.
- Low incidence of side-effects and absence of drug interactions were noted.
- Therapeutic doses do not impair driving ability or professional capacity.
Conclusions:
- Clobazam is a versatile daytime tranquilizer with a favorable safety profile.
- Its properties make it suitable for neuropsychiatry, other medical disciplines, and outpatient treatment.